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Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.

Hydrogels could lead to better treatments for wound healing without scars.

Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.

The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.

SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.

Scientists can now create skin with hair by reprogramming cells in wounds.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.

Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.

ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Different processes create patterns in skin and things like hair and feathers.

Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.