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Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Good preoperative assessment is crucial for safe and effective eyelid and brow cosmetic surgery.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.

Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.

Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.

Different PCOS types respond uniquely to infertility treatments, with some having lower pregnancy rates and higher risks of complications.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Altering maternal cortisol during pregnancy can improve wool growth in Merino sheep.

Cronkhite-Canada syndrome can be diagnosed without gastrointestinal polyps if there is severe mucosal atrophy and edema.

Lipids are important for healthy hair, but their exact role is not fully understood and needs more research.

Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.

Cicatricial alopecia causes permanent hair loss and is treated to relieve symptoms and stop progression.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.