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Hormonal treatments can improve acne, but they come with potential side effects and risks.

Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

A male with aromatase deficiency improved bone health with estradiol treatment.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.

A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Huoxue Bushen Mixture effectively treats female pattern hair loss by balancing hormones.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Many women with hair loss also have zinc deficiency, iron depletion, or thyroid issues.