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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

A new gene, JMJD1C, may affect testosterone levels in men.

New treatments for male hypogonadism are effective and should be personalized.

Applying a specific inhibitor lightens skin and hair color.

Testosterone may slow down wound healing and increase inflammation.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Prolactin may be important for skin growth and immune function.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Finasteride may cause male infertility, stopping it can help.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

The normal human prostate does not significantly affect blood DHT levels.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Finasteride causes lasting fertility decrease in rats.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Finasteride exposure harms tadpole reproduction and hormone balance.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.