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Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Hemp seed biomaterials may reduce hair loss and improve hair growth.

Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

The document advises health care providers on how to support transgender and gender-diverse youth with appropriate care and referrals.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.

Gender identity can be more diverse than just male or female.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.

Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Some nonsurgical hair loss treatments are effective, especially if started early.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

The microneedle patch with quercetin, zinc, and copper effectively promotes hair regrowth for androgenic alopecia.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.