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Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Spironolactone most effective for hirsutism, but has side effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

A new gene, JMJD1C, may affect testosterone levels in men.

Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Some common medications can harm male fertility, but many effects can be reversed.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.