September 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study mapped the development of the human pilosebaceous unit in prenatal scalp skin using multi-modal analysis, finding that epithelial-mesenchymal interactions guide cellular fate and validated tissue-patterning through a hair-bearing skin organoid model.
418 citations
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September 2012 in “Nature” This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.
January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)” In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.
22 citations
,
August 1999 in “Mechanisms of Development” This study identified two novel genes, pmg-1 and pmg-2, expressed in various skin and gland tissues and potentially involved in the differentiation of epithelial cells in epidermal appendages.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified intramembrane proteolysis as a key feature of Astrotactin2 maturation, providing insights into its role in planar cell polarity hair patterning.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study demonstrated that Tet2 and Tet3 enzymes are crucial for controlling gene expression related to hair differentiation in mice, suggesting DNA demethylation could be a new method for managing hair growth.
3 citations
,
September 2024 This study developed 3DEEP, a tissue clearing and spatial transcriptomic method, to map hair follicle development in a single time point from a 12-hour-old mouse, detailing molecular stages, signaling dynamics, and structural changes within developing follicles.
2 citations
,
January 2017 in “Indian dermatology online journal” This case study reports a 30-year-old woman with a mixed infection of white piedra and pediculosis capitis, indicating the difficulty in distinguishing between these conditions upon casual examination.
September 2024 in “Frontiers in Veterinary Science” In this study, researchers observed that introducing an Environmental Enrichment Program improved the reproductive and zootechnical performance of Calomys callosus rodents by enhancing reproductive indices, parental care, and overall health, including reduced non-infectious lumbar alopecia.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that deleting all three Tet genes in mice led to shorter hair shafts and altered hair types, with associated changes in gene expression and DNA hydroxymethylation.
April 2018 in “Journal of Investigative Dermatology” This study found that the loss of transcription factor Ovol2 in epidermal and hair follicle stem cells leads to migration defects, which are partially improved by deleting the EMT-inducing Zeb1.
3 citations
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November 1998 in “Pediatrics in review” This article reviews various dermatophyte infections, particularly tinea capitis, and discusses their clinical presentations, diagnosis, and treatment, but reports no new clinical findings.
12 citations
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June 2012 in “Revista da Sociedade Brasileira de Medicina Tropical” This case study reported a rare infection by Trichosporon inkin, causing white piedra in a family in Southern Brazil, emphasizing the importance of molecular tools for precise identification.
43 citations
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April 1996 in “Journal of Investigative Dermatology”
August 2025 in “Indian Dermatology Online Journal” This review discusses how metaphorical language in dermatology, particularly terms like "butterfly" and "moth," aids in diagnosing and understanding skin conditions by highlighting their distinctive clinical presentations and underlying pathophysiology.
3 citations
,
March 2025 in “Science Advances” This study found that the unique crest feather formation in Polish chickens is driven by a 195-bp duplication in the HoxC10 gene region, which alters gene expression by modifying the genomic structure, suggesting a mechanism for diverse integumentary appendages in birds.
April 2023 in “Journal of Investigative Dermatology” This study found that KROX20 is crucial for hair follicle development and epidermal homeostasis, as its deletion in skin epithelial cells led to hair loss and increased epidermal thickness.
3 citations
,
January 2022 in “Medical Mycology Journal” This study observed Malassezia hyphae in the keratotic plugs of healthy individuals, which contrasts with previous findings of these hyphae primarily in lesions of pityriasis versicolor patients.
21 citations
,
August 2011 in “BMB Reports” This study successfully established an immortalized human dermal papilla cell line that maintains characteristics of original cells without malignant transformation, potentially benefiting hair research.
January 2026 in “Buletin Veteriner Udayana” This study documented a case of Dipylidium caninum infection in a 4-month-old female dog, effectively treated with a deworming medication, resulting in significant improvement and no worms detected after five days. Routine deworming and maintaining hygienic conditions are recommended to prevent reinfection and transmission.
5 citations
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January 2022 in “Scientific reports” This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.
In a harbor seal from the Yellow Sea of Korea, this study found that alopecia-related lesions disappeared completely after treatment with internal and external ketoconazole, povidone iodine, cephalexin, and multivitamins over 8 months.
2 citations
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December 2024 in “BMC Genomics” In this study, researchers used transcriptome sequencing and bioinformatics analysis to identify important genes and pathways involved in the transition between hair growth phases, offering new insights into hair follicle cycle regulation and development.
May 2012 in “CRC Press eBooks” This review discusses the five functional subtypes of telogen effluvium proposed by Headington and reports no new experimental findings.
5 citations
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April 2019 in “Veterinary Dermatology” In this case series, cats infested with Lynxacarus radovskyi developed self-induced alopecia similar to flea allergic dermatitis, primarily affecting the perianal area.
22 citations
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July 1998 in “Journal of Investigative Dermatology” This study identified and characterized a gene called 4C32, which is expressed in the periderm of embryonic mouse skin and has a structure similar to keratin-associated proteins.
2 citations
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March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers used an evolutionary-rate-based method to identify genetic elements associated with reduced hair in mammals, finding a dichotomy between accelerated coding sequences and noncoding regulatory elements influencing hair growth.
2 citations
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October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that darker hair is typical in wetter regions for the Indriidae family, while within Propithecus, dark black hair is common in colder forests, suggesting evolutionary adaptations to environmental pressures.
1 citations
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April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study is the first to document alopecia in Guadalupe fur seals in the Northeast Pacific Ocean, finding that it may result from nutritional stress due to higher sea surface temperatures.
46 citations
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August 1977 in “Journal of Morphology” This study examined the unique structural features of sinus hair follicles in the shrew Sorex unguiculatus, which suggest a specialization for vibration sensing.