9 citations
,
July 2022 in “Journal of Biological Chemistry” This study in mice found that WWP2 facilitates odontoblast differentiation and dentin formation by targeting PTEN for degradation, thereby enhancing KLF5 activity, which may suggest its crucial role in dental development.
41 citations
,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the challenges and potential solutions in studying Demodex mites and their possible pathogenic role in human skin disorders but reports no new findings.
45 citations
,
October 2015 in “BMC Genomics” This study identified morphotype-specific gene expression patterns in feathers, enhancing understanding of the molecular and cellular processes involved in feather development and diversification.
7 citations
,
November 1997 in “Reproduction Fertility and Development” In this study, subcutaneous injections of murine epidermal growth factor in marsupial pouch young inhibited the formation of hair follicles and associated structures, altering normal follicle development.
7 citations
,
November 2014 in “Histochemistry and Cell Biology” This study found that mutant mice with the we/we wal/wal genotype exhibit significant defects in hair shaft structure and epidermis stratification, correlating with postnatal alopecia symptoms.
February 1999 in “The anatomical record” This study observed defects in hair cuticle cross-linking in some, but not all, mouse mutants with sparse or structurally unsound hair.
8 citations
,
April 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This case report details the first pediatric occurrence of naevus trichilemmocysticus, a newly defined type of organoid naevus.
12 citations
,
July 2011 in “Experimental Dermatology” This study found that mEGF ethosomal delivery systems mainly penetrated mice skin through the pilosebaceous unit and successfully induced hair follicles to transition from the telogen to anagen phase.
3 citations
,
March 2017 in “Pediatric Dermatology” This case report documents the first known instance of FOXN1 duplication linked to congenital hypertrichosis.
December 2025 in “Therya notes” In this study, researchers documented the first instance of alopecia in bats within the Puebla region, specifically affecting two Artibeus jamaicensis and one Choeronycteris mexicana, possibly linked to environmental stress from human activities interfering with their nutrition.
July 2024 in “Journal of Investigative Dermatology”
December 2012 in “Journal of dermatological science” This study observed that Langerhans cells and melanocytes migrated to hair follicle sites during human embryogenesis, suggesting that Langerhans cells acquire immunoregulatory properties there.
173 citations
,
August 2015 in “Developmental cell” This study characterizes gene expression patterns in embryonic hair follicle progenitors and their niche, identifying signaling pathways like axon guidance that may drive cellular rearrangements for hair follicle formation.
161 citations
,
June 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the switch-off of melanogenesis during the hair cycle in C57 BL-6 mice is a gradual and stochastic process starting in mid anagen VI, with specific biochemical markers indicating the transition to catagen.
3 citations
,
May 2024 in “Skin Appendage Disorders” This study observed that trichoscopy of long-lasting lesions in a chronic stage revealed specific features such as absence of follicular openings, cicatricial patches, and thick arborizing vessels.
25 citations
,
November 2020 in “Proceedings of the National Academy of Sciences” This study found that the HoxC gene cluster plays a critical role in the development of ectodermal organs, including hair and nails, with mammalian-specific enhancers increasing transcription levels during development.
July 2025 in “Genome biology” This study highlighted the effectiveness of HT-scCAT-seq as a tool for understanding gene regulation in single cells, offering insights into embryonic skin development and proposing a framework for exploring regulatory mechanisms in various biological and disease contexts.
5 citations
,
August 2012 in “Experimental Dermatology” In this study, Ser516 phosphorylation of Artemis was found predominantly in the outer root sheath keratinocytes of hair follicles, suggesting a role in regulating human epidermal appendages.
September 2025 in “Indian Dermatology Online Journal” This study explored the use of flower-inspired analogies in dermatology, highlighting how these vivid descriptions aid in diagnosing skin conditions by drawing parallels between clinical features and floral patterns, effectively blending scientific observation with artistic imagery.
15 citations
,
January 2009 in “Indian journal of dermatology, venereology, and leprology” This case report describes two instances of white piedra, a fungal hair infection, and notes successful treatment with oral itraconazole and topical ketoconazole in one patient.
January 2018 in “International Journal of Medical Reviews and Case Reports” This case study reports that a 6-year-old girl with pediculosis capitis experienced scalp pruritus, pustules, crusting, excoriation, and cicatricial alopecia but showed a good clinical response to permethrin and antibiotics, with no lice detected afterward.
March 2025 in “International Journal of Molecular Sciences” This study established a Krt24-CreERT2 mouse line targeting outer bulge hair follicle stem cells, finding these cells crucial for hair follicle development and repair, particularly following ionizing radiation exposure.
35 citations
,
September 2011 in “The Journal of Dermatology” This article discusses the trichoscopic diagnosis of temporal triangular alopecia, but reports no new clinical results.
October 2015 in “CRC Press eBooks” This article reviews the use of trichoscopy for diagnosing and monitoring various scalp conditions, but it presents no new experimental findings; the authors emphasize its precision in noninvasive evaluation.
This study found that somatosensory axons innervating Merkel cells in adult mouse skin exhibit significant plasticity, influenced by epithelial and neural factors, indicating a complex interaction in maintaining homeostasis.
10 citations
,
November 2010 in “Pigment Cell & Melanoma Research” This study found that epidermal melanocytes can regenerate hair follicles, whereas non-cutaneous or dermal melanocytes cannot, suggesting two distinct melanocyte lineages with potential implications for melanocyte-related diseases.
October 2014 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study identified a new subset of Ret-positive sensory neurons involved in itch perception, characterized by their unique expression profile and response to specific itch-inducing molecules.
7 citations
,
November 2010 in “Genesis” Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.