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Babies who gain weight quickly, especially in the first 3 months, may start puberty earlier.

Severe acne in a young girl may indicate underlying hormonal issues.

Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Certain maturity signs appear before and after the first release of sperm in boys.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Reduced AR gene methylation may cause early pubic hair growth in girls.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

The document concludes that common menstrual disorders affect adolescent women, with the normal menstrual cycle lasting 21 to 35 days.

A hair strand caused a rare case of limb strangulation in a teenage girl with autism, and the condition is not always linked to child abuse.

Higher fluoride levels may delay puberty in boys.

A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.