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Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.

Gene mutations can cause problems in male genital development.

New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

These skin conditions in African men need combined medical treatments and lifestyle changes.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

Higher fluoride levels may delay puberty in boys.

Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Bariatric surgery is safe and effective for treating adolescent obesity.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

Lasers have become safer and more effective for treating skin problems and hair removal.

A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.