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Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

MAIT cells may help fight COVID-19 but also contribute to severe inflammation.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.

The role of γδT-cells in causing alopecia areata remains unclear.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.

Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Children with autoimmune gastritis showed improved intestinal health over time and should be checked for other autoimmune conditions.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Fat-related cells are important for initiating hair growth.

Different types of skin cells play specific roles in development, healing, and cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.