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Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.

Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Erdr1 could be a new marker for diagnosing hair loss.

Different hair and scalp disorders cause hair loss or excess hair growth, with various treatments available depending on the specific condition.

The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.

Alopecia Areata significantly lowers quality of life and current treatments are inadequate, highlighting a need for better therapies and standardized treatment protocols.

COVID-19 may trigger or worsen rapid hair loss in alopecia areata.

Intralesional triamcinolone is the most effective treatment for alopecia areata, followed by excimer light therapy, and then topical minoxidil. The scalp responds better to treatment than the beard area.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.

New acne treatments show promise as alternatives to traditional therapies.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Simvastatin/ezetimibe did not effectively treat severe alopecia areata and caused side effects in some patients.

Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.

Most HIV patients develop skin symptoms that can indicate the stage of their disease.