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Digital gangrene can be a rare first sign of late-onset systemic lupus erythematosus.

Tofacitinib improved arthritis and partially improved hair loss in a lupus patient without side effects.

Low-dose oral and sublingual minoxidil seem safe for children with hair disorders.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

A girl initially thought to have a psychiatric disorder was later found to have a lupus-related condition, which improved with proper treatment.

A man had bad reactions to a hair loss treatment called DNCB.

Combining hydroxychloroquine and pimecrolimus can effectively treat hair loss from discoid lupus.

Systemic immunotherapies are used for immune-related hair loss but not usually for genetic hair loss, unless the patient has both conditions.

A patient with both bullous lichen planus and systemic lupus erythematosus showed improvement with treatment.

Both topical and oral finasteride are equally effective for treating male pattern baldness.

Systemic cyproterone acetate and 5% topical minoxidil are effective and safe for treating female pattern hair loss.

Pediatric systemic lupus erythematosus is a severe autoimmune disease in children requiring early diagnosis and comprehensive management.

The document concludes that systemic therapy is becoming more important in treating head and neck cancer, with new treatments showing promise.

Using minoxidil and tofacitinib together can effectively treat severe hair loss.

The analysis aims to identify the most effective and safest treatments for alopecia areata.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.

Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.

A mix of methotrexate, corticosteroids, and topical minoxidil effectively treated severe total body hair loss, but caused stretch marks and needs long-term monitoring.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Systemic treatment is necessary for tinea capitis in children, with griseofulvin preferred for Microsporum infections.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.

A 5-year-old boy's skin condition improved with systemic valganciclovir after a cardiac transplant and immunosuppressive therapy.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.