TLDR Combining hydroxychloroquine and pimecrolimus can effectively treat hair loss from discoid lupus.
A 46-year-old woman with localized scarring alopecia due to discoid lupus erythematosus (DLE) experienced significant hair regrowth and resolution of alopecia after an eight-week treatment with oral hydroxychloroquine (200 mg twice daily) and topical pimecrolimus (1% cream). Initial treatments with triamcinolone injection, tacrolimus ointment, and clobetasol ointment were ineffective. This case highlights the potential effectiveness of combining systemic hydroxychloroquine with topical pimecrolimus for treating DLE alopecia, suggesting a promising approach for future management of this condition.
46 citations,
June 2018 in “American Journal of Clinical Dermatology” Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.
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3 citations,
March 2021 in “Clinical, Cosmetic and Investigational Dermatology” Early treatment of Lupus Erythematosus Alopecia can prevent permanent hair loss, and various medications are effective.
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Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.
January 2012 in “Springer eBooks” Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
July 2018 in “Elsevier eBooks” Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.
