1 citations
,
July 2021 in “Frontiers in Oncology” This study found that patient-reported outcomes were similar between neoadjuvant endocrine therapy and chemotherapy in premenopausal breast cancer patients, but future perspective was significantly better with endocrine therapy.
August 2026 in “Cosmoderma” This review identifies sebaceous gland disorders as key indicators of hormonal imbalances, detailing how various hormones affect sebaceous function, and emphasizes a multidisciplinary approach to improve diagnosis and management by integrating endocrine, metabolic, and dermatologic insights.
February 2026 in “Journal of the American Academy of Dermatology” Estrogen is not recommended for menopausal hair loss due to insufficient evidence.
December 2025 in “International Journal of Innovative Technologies in Social Science” This review suggests that while estrogen-targeted therapies may improve skin quality in postmenopausal women, systemic risks limit hormone replacement therapies, and more research is needed for localized treatments.
August 2006 in “Experimental dermatology” This review discusses hormone-related hair disorders and explores potential therapies, including microparticle-based drug delivery systems, without providing new clinical findings.
76 citations
,
November 2009 in “Medical Clinics of North America” This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.
18 citations
,
August 2019 in “Clinical breast cancer” This meta-analysis found that in postmenopausal women with a history of breast cancer, 8 weeks of vaginal estrogen therapy while on aromatase inhibitors did not result in systemic absorption of sex hormones, suggesting potential safety for treating vulvovaginal atrophy in this context.
100 citations
,
July 2004 in “The Journal of Sexual Medicine” This article reviews how various hormones may affect female sexual function and provides recommendations for diagnosing and treating endocrinologic sexual difficulties, but it reports no new clinical results.
6 citations
,
January 2016 in “Menopause” Estrogen deficiency, like after menopause or certain surgeries, leads to faster skin aging and health issues.
3 citations
,
April 2019 in “Journal of the Endocrine Society” This case report describes a rare instance of Satoyoshi syndrome in a 27-year-old Asian American woman, notable for her normal ovarian function despite typical syndrome features.
2 citations
,
September 2025 in “Cosmetics” This narrative review synthesized current research on hormonal therapies in cosmetic dermatology, finding they offer promising, evidence-based applications for conditions like aging skin, acne, and melasma, but noting that safety and personalized treatment approaches are essential for responsible clinical use.
1 citations
,
November 2021 in “Lara D. Veeken” This article discusses the interaction between menopause and rheumatic diseases, emphasizing the need for rheumatologists to recognize menopausal symptoms and consider hormone replacement therapy in patient care, but it provides no new experimental results.
September 2023 in “Gynäkologische Endokrinologie” This review discusses how the hormonal changes of menopause affect skin and hair, highlighting improvements in skin symptoms like dryness and reduced wound healing with estrogen supplementation, and advises healthcare providers to consider broader potential benefits of menopausal hormone therapy when consulting patients.
12 citations
,
October 2018 in “International Journal of Women's Dermatology” This review discusses lesser-known concerns in transgender dermatology, including neovaginal issues, neoplastic and autoimmune conditions, and the effects of unapproved injectable substances, but reports no new clinical findings.
187 citations
,
December 2005 in “Experimental Dermatology” This article discusses the role of estrogens in skin aging and reports no new findings; it highlights the potential of selective ER modulators to improve skin health without systemic side effects.
18 citations
,
August 2012 in “Journal of The American Academy of Dermatology” This report describes a case where a sex reassignment patient on estrogen therapy experienced complete hair regrowth on a previously fully alopecic scalp.
10 citations
,
January 2014 in “Journal of Mid-life Health” This article reviews dermatological problems associated with estrogen deficiency in menopausal women and highlights the importance of dermatologist and gynecologist collaboration, but reports no new clinical results.
67 citations
,
January 2007 in “Climacteric” This article discusses the impact of estrogens on skin aging, highlighting the potential benefits and unresolved effectiveness of alternatives like phytoestrogens and selective estrogen receptor modulators; it reports no new clinical results.
December 2025 in “Pakistan Journal of Health Sciences” This systematic review found that estrogen deficiency in postmenopausal women leads to structural and symptomatic changes in genital and cutaneous tissues, with local estrogen therapy providing short-term benefits, while evidence for device-based treatments remains limited and requires larger trials.
15 citations
,
July 2020 in “Dermatologic Therapy” This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.
120 citations
,
October 2007 in “Clinical Interventions in Aging” This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.
4 citations
,
October 2007 in “Dermatologic Clinics” This review discusses the roles of glucocorticoid and sex hormone receptors in the skin and their clinical importance, but reports no new research findings.
22 citations
,
November 2018 in “Breast Cancer Research and Treatment” In this review, researchers found no evidence of interactions between 5α-reductase inhibitors or spironolactone and endocrine therapies for breast cancer, with no consistent changes in estrogen levels or increased breast cancer risk associated with spironolactone usage.
January 2011 in “Padua Research Archive (University of Padua)” This study suggests that human skin locally synthesizes active sex steroid hormones, impacting inflammation, cell behavior, and wound healing, with potential implications for therapies in aging and impaired wound recovery.
515 citations
,
April 2003 in “Endocrine Reviews” This review discusses hormone replacement therapy for menopausal women, emphasizing DHEA's unique ability to convert into sex steroids only in targeted tissues, and reports no new clinical results.
18 citations
,
June 2010 in “Current medicinal chemistry” This review discusses current treatment options for hirsutism, emphasizing the importance of combining therapies for better outcomes, but reports no new clinical findings.
22 citations
,
January 2004 in “Dermatology” This article discusses the use of topical estrogen therapy for androgenetic alopecia in menopausal females and reports no new clinical results.
December 2025 in “ADMET & DMPK” This review synthesizes recent research to propose a precision framework for treating androgenetic alopecia and alopecia areata based on genetic insights and pathway biology, highlighting the roles of androgen-receptor signaling, immune dysregulation, and emerging therapies like regenerative medicine and AI-assisted diagnostics.
December 2023 in “Migration letters” This meta-analysis reviewed 25 studies and suggested that herbal interventions could improve reproductive health in women with PCOS, showing benefits across measures such as Body Mass Index, hirsutism, and insulin levels, although results were mixed for fasting glucose and FSH levels.
75 citations
,
November 2016 in “Medicines” This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.