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This study found that COVID-19 infection disrupts spermatogenesis, alters testicular cell populations, and may impact male fertility by causing long-term changes in testicular function and reduced sperm quality, as observed even in patients who have recovered from the acute phase of the infection.

In this study using mouse models, researchers found that elevated IL-17a in aged olfactory epithelium impairs olfactory function, while IL-17a inhibition promotes regeneration and mitigates age-related decline.

This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.

In this study, researchers developed a mathematical model of outer hair cell hair bundles that replicates experimental responses to mechanical stimuli, providing insights into the stimulus-dependent adaptation mechanisms and the functional significance of their three-row stereocilia configuration in mammalian hearing.

In this study, radial shockwave therapy significantly improved muscle spasticity, ankle range of motion, and functional abilities in children with spastic cerebral palsy, suggesting it may help them achieve greater autonomy in daily activities.

This study found that rat hair-follicle-associated pluripotent stem cells can be successfully differentiated into beating atrial and ventricular cardiomyocytes by using specific combinations of growth factors and inhibitors in culture, demonstrating their potential to form functional myocardial fibers similar to adult heart cells.

This review discusses the effects of neuroactive testosterone metabolites on CNS functions and suggests their potential as therapeutic options for neurological disorders, but reports no new clinical results.

This study found that the spinal projection of afferents innervating slowly adapting mechanoreceptors had a greater rostrocaudal extent and number of boutons compared to those innervating rapidly adapting mechanoreceptors.

This review discusses the varied roles of Wnt7a in development, tissue homeostasis, and cancer, reporting no clinical results; the authors emphasize the need for further investigation on its roles in inflammation and fibrosis.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

This review discusses the potential clinical benefits and functional properties of taurine as a conditionally essential amino acid, noting its presence in energy drinks, but reports no new experimental results.

In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.

This article discusses the plasticity of δ-GABAARs during altered neurosteroid production and its effects on neuronal network function, with potential therapeutic strategies proposed for several neurological and psychiatric disorders.

This study found that single-crystal magnesium samples smaller than 100 nm exhibited increased plastic deformation due to greater activation of nonbasal planes as local flow stresses approached 2 GPa.

In this pilot study, no significant differences were observed between memantine and placebo groups in young adults with Down syndrome on the primary memory outcomes, but some improvement was noted in a secondary measure.

This study found that long-term use of triterpenoids from Ganoderma lucidum may improve brain function and alleviate aging-related issues in normal and Alzheimer's mouse models.

This review discusses current knowledge about the TRPV3 ion channel's role in skin functions and diseases, highlighting its potential as a therapeutic target for pain and itch, though suitable ligands are limited.

This study found that corticosterone promotes neurosteroid synthesis in hippocampal neurons, which can lead to ethanol-mediated synaptic dysfunction even at moderate ethanol levels, potentially contributing to stress-related cognitive impairment from alcohol.

This review discusses how polymers can be customized to develop biomaterials that mimic the extracellular matrix, exploring their potential in biomedical and biotechnological applications by triggering cell functions similar to natural physiological systems.

This study reports the development of a novel protocol to purify human TRPV3 ion channels, revealing functional properties and differences in ligand interactions, enabling further structural and functional research.

This article discusses the role of zinc in reducing depression severity and reports no new research findings, emphasizing the need for further investigation into its therapeutic potential.

This article reviews the role of nitric oxide in skin health, including its influence on immune responses and potential therapeutic applications for contact dermatitis, but reports no new clinical results.

This study in neonatal rats found that inhibiting neurosteroid synthesis with finasteride unexpectedly reduced the severity and duration of neonatal seizures following birth asphyxia, maintained cognitive functions, but increased anxiety-like behaviors, highlighting a complex role of neurosteroids in hypoxic-ischemic encephalopathy outcomes.

This research suggests that the drugs trazodone and chlorpromazine, which have effects on specific receptors, may help restore libido synaptic circuits and potentially treat sexual dysfunction associated with post-SSRI and post-finasteride syndromes.

This study found that subchronic finasteride treatment in male rats altered neuroactive steroid levels and steroid receptor expression in the brain, with some changes persisting after drug withdrawal.

This review explores potential new roles for Merkel cells, including involvement in magnetoreception, fingerprint formation, and transmitting environmental information, but reports no experimental results.

This study found that SK2 channels in sensory terminals of rat muscle spindles and hair follicles may play a crucial role in modulating mechanosensory transduction by influencing receptor potentials through Ca2+-activated K+ currents.

In this study, germ-free male mice showed altered levels of certain neuroactive steroids in the brain and periphery, suggesting microbiota may influence neuroendocrine pathways that support brain functioning.

This study suggests that inhibitors of steroidogenic enzymes may have therapeutic potential for certain behavioral disorders linked to dopaminergic hyperfunction, despite concerns about their endocrine impacts.

In this study, researchers identified the PLD-mGluR protein in primary mechanosensory terminals as the homomeric GluK2 kainate receptor, functioning purely metabotropically, which is suggested to be common to various sensory endings.