144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
141 citations,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
139 citations,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
139 citations,
November 2015 in “Journal of Advanced Research” Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
138 citations,
August 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
138 citations,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
138 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
136 citations,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
135 citations,
January 2016 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
134 citations,
January 2019 in “American journal of clinical dermatology” Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
133 citations,
June 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
132 citations,
February 2013 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
131 citations,
August 2000 in “International Journal of Dermatology” Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
131 citations,
May 2015 in “Experimental Dermatology” Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.
130 citations,
November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
129 citations,
February 2007 in “Otology & Neurotology” Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.
129 citations,
November 2005 in “Internal Medicine Journal” Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.
127 citations,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
127 citations,
January 2013 in “PLOS ONE” Probiotic bacteria improved skin and hair health in aged mice.
127 citations,
December 2005 in “Experimental Dermatology” Stress can stop hair growth in mice, and treatments can reverse this effect.
126 citations,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
125 citations,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
125 citations,
September 2019 in “Journal of Clinical Immunology” Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
122 citations,
November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
120 citations,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
120 citations,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
120 citations,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
118 citations,
October 2005 in “Journal of Ethnopharmacology” Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.