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This study found that exogenous ochronosis from hydroquinone use in melasma treatment has distinctive dermatoscopic features that may aid in diagnosis without needing a biopsy.

This study found that specific enzymes could be detected in fresh hair sheath cells, with most remaining detectable in older cells, except for Adenylate kinase and Esterase D.

This study found that in a mouse model of bronchopulmonary dysplasia, minoxidil administered at 50 mg/kg/day did not impact lung development or inhibit lysyl hydroxylation.

This study found that stabilizing HIF1A in hair follicle cells promoted a shift to glycolysis, potentially reducing oxidative stress and promoting hair growth, particularly in balding dermal papilla cells.

This study found that mitochondrial reactive oxygen species are crucial for normal epidermal differentiation and hair follicle growth, as demonstrated by impaired development in mice lacking these signals due to a keratinocyte-specific TFAM deficiency.

This study found that overexpression of the enzyme spermidine/spermine N1-acetyltransferase in mice was associated with increased fat oxidation and a leaner phenotype, while knock-out mice exhibited increased fat accumulation.

This review identifies cysteine's central role in hair growth and its potential impact on Alopecia Areata's pathogenesis, suggesting examination of cysteine metabolism might clarify the disease's underlying mechanisms and lead to new treatments.

This study suggests that minoxidil activates PGHS-1, which may explain its hair growth-stimulating effects and could aid in designing more potent hair growth-promoting drugs.

This study identifies mutations in the SRD5A3 gene as a cause of a new type of congenital disorder of glycosylation, impacting mental, ophthalmologic, and cerebellar functions.

This study found that enzymatic conversion of Arg-51 in S100A3 protein to citrulline promotes homotetramer assembly, potentially increasing Ca²⁺ binding required for hair cuticular barrier formation.

This study found that a sunscreen with oxothiazolidine and δ-tocopheryl glucoside provided complementary oxidative protection, with immediate but brief effects from oxothiazolidine and prolonged effects from the slower-absorbing δ-tocopheryl glucoside.

This study found that chondroitin sulfate levels were higher than hyaluronic acid in skin and hair follicle samples, with the highest concentration observed in prekeratin of hair follicles and wool fibers.

This study explored how modifying the 8-substituent of 8-bromobenzoquinolinone affects its selectivity in inhibiting both 5 alpha-reductase isozymes in the scalp.

This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.

This study found that cysteic acid generation during hair bleaching is diffusion-controlled, increasing with the square root of bleaching time, in both cuticles and cortex of human hair fibers.

This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.

In laboratory models of human skin, this study found that treating with resveratrol significantly increased glutathione levels, potentially enhancing the skin's antioxidant defenses.

This study provided the crystal structure of the human steroid 5α-reductase 2 enzyme and identified key molecular mechanisms for testosterone reduction and finasteride inhibition, aiding in understanding disease-causing mutations and potentially facilitating new drug development.

In this study, researchers found that oxidative stress and mitochondrial dysfunction are correlated with the severity of both androgenetic alopecia and alopecia areata, revealing specific differences between alopecia forms, which may serve as important pathogenetic and prognostic indicators.

In this study, researchers highlighted the potential of antioxidative nanozymes as a promising treatment for ischemic stroke, due to their stability, cost-effectiveness, and ability to regulate ROS-induced inflammation, positioning them as a noteworthy alternative to natural enzymes like catalase and superoxide dismutase.

This study found that procyanidin oligomers bind to keratin and inhibit oxidative hair damage, suggesting their potential use in protective hair care products.

In their 1957 study, Neuman and Neuman suggested that magnesium deficiency may inhibit the ion exchange process required for calcium ions to enter extracellular fluid, potentially affecting calcium mobilization.

This research found that Leydig cells significantly rely on synthesizing omega-6 HUFAs to support male steroid hormone production, highlighting a new role for these fatty acids in the male reproductive system.

This study developed a simple and rapid method using silver nanoparticles to detect minoxidil concentration in hair-growth formulations, demonstrating a detection limit of 0.35 mM.

This article reviews recent advances in the synthesis of oxasteroids and reports no new experimental results.