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Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

High androgen levels in young women with PCOS are linked to higher blood pressure.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Flutamide may slightly improve hair loss in women, but finasteride does not work.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Minoxidil promotes hair growth but stops working when discontinued.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Minoxidil effectively treats severe hypertension, but watch for side effects.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Minoxidil helps hair cells live longer and grow longer.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.