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Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

The effects of estrogen on human hair growth are unclear and need more research.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.