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Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Anorexia nervosa may cause a hair defect called pili torti due to malnutrition and high vitamin A levels.

Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Hair's structure and properties change with pH; acidic pH maintains strength and less swelling, while alkaline pH increases water content and swelling.

Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.

The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

A person with Turner Syndrome showed severe schizophrenia that didn't respond to treatment and had brain shrinkage.

Darier-White disease causes skin and nail issues, starts around age 20, worsens until 40-50, and has poor treatment options.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

Hormonal differences affect male pattern baldness.

The document concludes that accurate diagnosis of hair loss in children is crucial due to limited treatment options and the condition's psychological impact.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

OCT can effectively examine and reveal details about human hair and scalp conditions.

Hair microscopy is a useful and affordable way to diagnose hair disorders.

New treatments targeting specific genes show promise for treating keratin disorders.

Alopecia areata involves immune response and gene changes affecting hair loss.

Alopecia Areata causes significant structural and compositional changes in hair.