10 citations
,
January 2011 in “Journal of biomedical optics” This study found that optical coherence tomography provides highly reproducible and less variable measurements of hair shaft thickness compared to standard light microscopy, offering a promising noninvasive tool for clinical practice.
97 citations
,
December 2021 in “Cells” This review outlines key considerations for designing fluorescence microscopy experiments in cell biology, discussing the importance of hardware availability, suitability of biological models, and imaging agents to achieve high-resolution and informative images.
May 2024 in “International Journal of Cosmetic Science” This study found that using near-infrared optics, specifically in the second NIR window, allows for effective noninvasive evaluation of intra-hair damage caused by cosmetic treatments, demonstrating distinct damage types and changes in hair condition due to chemical or thermal processes.
This study suggests that a portable OCT system may be useful for the clinical diagnosis and evaluation of skin diseases and laser treatment outcomes.
10 citations
,
November 2019 in “Cold Spring Harbor Perspectives in Biology” This review discusses how recent advances in live imaging have revealed the dynamic and adaptable nature of stem cells during various biological processes, and reports no clinical results.
April 2016 in “Journal of The American Academy of Dermatology” The study suggests low-cost videomicroscopes may identify some hair shaft features but are unreliable for comprehensive scalp trichoscopy compared to standard devices, due to color and resolution limitations.
25 citations
,
December 2008 in “Journal of Dermatological Case Reports” In this study, R-CSLM showed promise in evaluating hair shaft diseases by providing high-quality images of hair structures, although further development is necessary for follicle and perifollicular area analysis.
August 1989 in “Proceedings ... annual meeting, Electron Microscopy Society of America/Proceedings, annual meeting, Electron Microscopy Society of America” This microscopy study examined the non-keratinous regions of human hair fibers, revealing detailed morphology that could help understand how external influences affect hair structure.
This research explores the use of serial block-face scanning electron microscopy to model the complex architecture of sheep wool fibres, focusing on the role and distribution of para- and ortho-cortical cells in determining wool curliness, though the mechanism remains unclear.
1 citations
,
June 2020 in “Unisa Institutional Repository (University of South Africa)” This study found that low power red laser therapy, combined with antiretroviral drug efavirenz, significantly reduces HIV-1 infection in TZM-bl cells to undetectable levels.
August 1994 in “Journal of Dermatological Science”
30 citations
,
September 2009 in “Seminars in Cutaneous Medicine and Surgery” This review outlines how dermoscopy enhances diagnostic accuracy by up to 30% compared to unaided visual inspection and explores its potential as a research tool without presenting new research findings.
January 2022 in “Skin appendage disorders” In this study, the researchers found that trichoscopy can effectively visualize scalp micropigmentation, identified by homogenous, grey to black circular dots similar to closely cut hair, potentially reducing the need for invasive procedures.
316 citations
,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.
9 citations
,
November 2006 in “Journal of Microscopy” This study using an apertureless scanning near-field optical microscope found that dye restricted to hair's periphery remains mainly on the surface and in the endocuticle.
10 citations
,
January 2015 in “Skin appendage disorders” This study suggests that while low-cost videomicroscopes can correctly identify hair shaft alterations, they may be unreliable for detailed follicular and perifollicular trichoscopic examination compared to standard videodermatoscopes.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” In this study, researchers suggest that digital microscopy using visible light could offer a more objective approach to diagnosing hirsutism by quantifying terminal hair, with future research needed to assess its usefulness in women with the condition.
1 citations
,
June 2012 in “Revista de la Escuela de Medicina Legal” This study found that using a microscope can effectively distinguish between human and animal hair based on microscopic characteristics, making it a critical tool in forensic investigations.
13 citations
,
March 2021 in “Frontiers in oncology” This review discusses the strong correlation between reflectance confocal microscopy images and horizontal histopathology in diagnosing skin tumors, highlighting the reliability of this non-invasive technique; no new clinical results are reported.
45 citations
,
December 2004 in “Forensic Science International” This study reports that using laser microdissection to isolate telogen hair follicles significantly improves DNA extraction efficiency for STR typing, reducing contamination from keratin.
April 2016 in “Journal of The American Academy of Dermatology” This study suggests that low-cost videomicroscopes may not be reliable for diagnosing hair and scalp disorders due to limitations in color quality and resolution.
March 2026 in “Mendeley Data” This abstract presents supplementary trichoscopy images for alopecia areata and scarring alopecia but reports no clinical findings.
27 citations
,
February 2003 in “Cell and Tissue Research” This study found that FM dyes are effective markers for tracing live Merkel cells in in vitro experiments, as they remain visible for at least seven days and highlight cell shape better than quinacrine.
June 2020 in “Journal of Investigative Dermatology” This study found that human hair follicle dermal papilla cells and keratinocytes self-assembled differently in 3D spheroid co-cultures, providing insights into cell distribution and organogenesis during skin regeneration.
7 citations
,
January 2015 in “PubMed” This study found that ultrasound biomicroscopy can effectively visualize hair follicles in alopecia areata patients, with no significant difference compared to histopathological measurements of follicle number and width.
4 citations
,
November 2003 in “Hair transplant forum international” This abstract mentions that using magnification during follicular unit graft dissection in hair restoration is known to reduce transection and increase graft yield, but does not report on new findings itself.
September 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that high-speed optical coherence tomography may be a promising non-invasive tool for analyzing human hair conditions.
1 citations
,
December 2005 in “Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale” This study used Scanning Electron Microscopy to analyze South American mummy hair, revealing high levels of sulfur, calcium, and potassium, highlighting SEM's utility in anthropological investigations.
2 citations
,
January 2020 The document describes a method for preparing hair for microscopy by embedding it in plastic, cutting it, and storing it cold before imaging.
28 citations
,
June 2003 in “Applied immunohistochemistry & molecular morphology” This study demonstrated that combining cell conditioning with mild protease digestion enhanced the visualization of versican mRNA in formalin-fixed mouse skin tissue sections compared to using either technique alone.