September 2021 in “Physiology News” The abstract does not provide any research findings or conclusions to summarize, focusing instead on color and logo specifications.
288 citations
,
January 2001 in “Journal of Biological Chemistry” In this study, the disruption of Gh/tissue transglutaminase in mice did not affect viability but reduced thymocyte viability and fibroblast adhesion, suggesting its role in cell stabilization and extracellular matrix interactions.
182 citations
,
May 2003 in “Development” This study found that Myc activation in mouse epidermis impairs keratinocyte adhesion and motility by downregulating extracellular matrix and cytoskeleton proteins, affecting hair lineage differentiation.
162 citations
,
July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
139 citations
,
August 2006 in “Molecular and Cellular Biology” This study found that Rac1 is crucial for maintaining the integrity of hair follicle structure but is not needed for skin epidermis maintenance in mice.
130 citations
,
January 2017 in “International journal of nanomedicine” This study found that Na CMC hydrogel loaded with PEG-coated silver nanoparticles demonstrated superior antibacterial and wound-healing efficacy compared to commercial silver sulfadiazine cream in a wound-healing model.
91 citations
,
August 2019 in “Frontiers in Microbiology” This study found that the RpoN/RpoS pathway regulates gene expression in Borrelia burgdorferi, influencing its ability to persist in mammals and adapt to different hosts.
87 citations
,
August 2017 in “Scientific Reports” This study found that PCL-based nanofiber scaffolds enhanced cell proliferation and extracellular matrix deposition, suggesting they show promise as a cell delivery system for improving skin wound healing.
69 citations
,
April 1998 in “Journal of The American Academy of Dermatology” In this study, single hair grafting was reported to be an effective treatment for localized/segmental vitiligo, notably in hairy skin areas, with repigmentation observed in 82% of those cases.
63 citations
,
October 1972 in “British Journal of Dermatology” Women with thinning hair have thinner hair strands than women without hair loss.
60 citations
,
June 1997 in “Journal of The American Academy of Dermatology” This review discusses the basic biology of apoptosis and its relevance to skin diseases, without presenting new research findings.
55 citations
,
April 2010 in “Cancer and Metastasis Reviews” This article discusses the complex role of TGFβ in cancer progression, highlighting its dual function as both a tumor suppressor in early stages and a promoter in later stages, without reporting new results.
55 citations
,
January 1988 in “Dermatology” This study observed that 6.7% of patients treated with diphencyprone for alopecia areata developed vitiligo, with varying patterns and improvements noted among cases.
55 citations
,
February 1985 in “Archives of Dermatology” In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.
46 citations
,
January 2002 in “Paediatric drugs” This review discusses treatment options for tinea capitis in children and reports no new clinical results; the authors recommend newer antifungal agents in cases of griseofulvin treatment failure.
46 citations
,
January 1988 in “PubMed” This study found that Demodex mites may transport Microsporum canis spores on human skin, suggesting a potential role in microbial movement despite typically being considered harmless.
36 citations
,
October 2016 in “Medical mycology” This study at Mbarara University of Science and Technology found that T. violaceum is the most common cause of tinea capitis in children in Western Uganda, and systemic therapy is preferred over topical treatments for effective management due to the nature of the infection.
33 citations
,
September 2018 in “Frontiers in Microbiology” This study demonstrated that human hair shafts can inhibit the growth of Gram-positive bacteria but have no effect on Gram-negative bacterial growth, offering insights into hair and scalp health.
30 citations
,
August 1998 in “International Journal of Dermatology” This study found that systemic corticosteroids led to satisfactory hair regrowth in 38.9% of severe alopecia areata patients, but hair fall occurred upon therapy discontinuation or tapering.
30 citations
,
February 1994 in “Journal of Cutaneous Pathology” This case study highlights that breast cancer may present as alopecia refractory to usual treatments, indicating the need for consideration of underlying malignancy in such cases.
29 citations
,
January 2005 in “Journal of Long-Term Effects of Medical Implants” This article reviews the clinical characteristics and treatment options for various common bacterial skin infections but presents no new clinical results.
27 citations
,
November 2020 in “International Journal of Dermatology” This review examined dermatologic symptoms associated with COVID-19 in 2,560 patients, with chilblains/pernio-like lesions being the most common, suggesting these symptoms may aid in early identification of cases.
25 citations
,
September 1995 in “Biochemistry and Cell Biology” This study found that high levels of human cytokeratin 16 expression in transgenic mice lead to skin lesions and altered keratinocyte structure, suggesting potential implications for human skin disorders and wound healing.
24 citations
,
February 2021 in “Dermatology and Therapy” This study reported a significant relapse in alopecia areata among patients infected with COVID-19, possibly due to the infection's inflammatory response and stress from quarantine.
22 citations
,
September 1993 in “Archives of Dermatology” This case report details a 4-year-old girl who developed a fever and widespread papular, pruritic rash resembling a heat rash, with a progression to thick, scaly patches but had sterile blood and urine cultures.
13 citations
,
March 2018 in “Journal of Sociology” This article argues that the promissory discourse in the anti-ageing treatments market exploits societal anxieties about ageing, but its long-term sustainability is questionable as many promises remain undeliverable.
12 citations
,
January 2018 in “Biomaterials Science” This study observed that dermal papilla cell aggregates showed increased viability and gene expression on softer 3D substrates, indicating the importance of substrate stiffness in cellular behavior.
12 citations
,
May 2015 in “Journal of the National Comprehensive Cancer Network” This article provides a narrative on managing dermatologic side effects from cancer therapies and suggests strategies that oncologists could adopt, but it reports no new clinical findings.
11 citations
,
July 1984 in “Australian Veterinary Journal” This study found that povidone iodine, thiabendazole ointment, captan ointment, and Burroughs Wellcome Ringworm Ointment were effective against Trichophyton equinum var. autotrophicum in horses, but large-scale use may be limited by practicality and cost.
10 citations
,
June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.