2 citations
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June 2024 in “Parasites & Vectors” This study provides insights into how chronic T. gondii infection might affect testicular tissue and suggests a potential impact on male fertility.
This study found that fibroblasts from highly regenerative mammals, such as spiny mice and rabbits, exhibit unique metabolic characteristics, including a preference for glycolysis and specific mitochondrial features, which may contribute to their resistance to oxidative stress and support tissue regeneration.
In this study, three cases of young men using finasteride for five years showed altered sperm morphology and motility issues, with partial improvement observed after discontinuation.
11 citations
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November 2023 in “Journal of Functional Biomaterials” This study investigated nanocomposite scaffolds made from alginate, chitosan, and graphene oxide to promote the proliferation of spermatogonial stem cells, finding the ALGCS/GO30 scaffold to be particularly effective due to increased proliferation markers and PLZF protein expression compared to controls.
3 citations
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February 2017 in “Archives of Medical Science” This study found that finasteride treatment in male rats may lead to changes in connexin 43 expression in the testes of their offspring, potentially affecting spermatogenesis.
January 2022 in “European journal of anatomy” This study reports a rare case of polyorchidism in a 96-year-old male cadaver, suggesting a new classification based on anatomical and histological findings to aid in accurate diagnosis.
1 citations
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December 2011 in “EFSA Journal” This opinion from the EFSA Panel concludes that the health claim regarding spermidine prolonging the anagen phase of the hair cycle does not meet regulatory criteria as it is related to disease treatment.
35 citations
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October 2004 in “Biology of Reproduction” This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.
December 2023 in “Urogenital tract infection” Seminal bacteria can lower sperm quality in subfertile men.
15 citations
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January 1999 in “Reproduction Fertility and Development” This study conclusively demonstrated that in Merino fetuses, secondary follicle initiation is completed several weeks before birth, with a peak 16 days prior and lower levels observed at and after birth.
January 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This review reports an increasing trend in sperm DNA fragmentation research over the past 20 years, with a focus on lifestyle, asthenozoospermia, and varicocele, and highlights the TUNEL technique as widely used.
11 citations
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January 1977 in “Archives of dermatological research” Mouse tail skin has different keratinization near hair follicles and scales.
8 citations
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October 2024 in “Developmental Cell” 6 citations
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January 2022 in “BIO-PROTOCOL” This article provides a protocol for live imaging of C. elegans germline stem cells, highlighting their potential for studying mitosis and other cell processes, but does not report new experimental findings.
2 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that SYP123 and VAMP727 are involved in the secretion and transport of inner cell wall components, which is crucial for hardening the root hair shank in Arabidopsis.
1 citations
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May 2007 in “PubMed” This case study of a subfertile couple highlighted the importance of considering haemochromatosis, particularly involving the C282Y mutation of the HFE gene, in patients with endocrine disorders linked to hypogonadism.
29 citations
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November 2011 in “Veterinary pathology” This study reports that eccrine sweat glands in mice predominantly develop on the footpads, offering a reference for skin research involving genetically engineered mice.
January 2013 in “Tampere University Institutional Repository (Tampere University)” This study observed that Tudor-SN protein may play a significant role in the immune system and that polyamines can influence hair growth in a mouse model.
3 citations
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June 2011 in “EFSA Journal” This review evaluates health claims regarding spermidine's contribution to normal hair growth and finds no evidence to support a cause-and-effect relationship.
1 citations
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March 2018 in “Cureus” This review discusses scrotal rejuvenation procedures and treatments, highlighting a growing interest in this area due to increased awareness of potential scrotal conditions and available interventions.
1 citations
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July 2021 in “Current Issues in Molecular Biology” This study found that finasteride treatment of male rats led to changes in their male offspring's testicular gene expression, potentially affecting sperm function in response to odorant-like signals.
2 citations
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December 2001 in “PubMed” In this review, the authors found no evidence of harmful pregnancy outcomes from exposure to finasteride, and report that handling the medication poses negligible risk to a fetus.
2 citations
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October 1999 in “The Journal of Urology” January 2016 in “ISBN: 978-84-608-9184-0”
37 citations
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January 1991 in “Reproductive Toxicology” The study observed that finasteride reduced fertility in male Sprague-Dawley rats by impairing the formation of copulatory plugs, an effect considered specific to rats and not applicable to species without this reproductive feature.
June 2018 in “The Journal of Sexual Medicine” In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.
47 citations
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August 2012 in “Cell Cycle” This study found that multipotent, nestin-expressing stem cells from the upper part of hair follicles can proliferate significantly and differentiate into various cell types, showing potential for nerve and spinal cord repair.
January 2014 in “theses.fr (ABES)” In this research, Sertoli cell line model ST38c demonstrated that the androgen receptor regulates hormone pathways through specific coregulators, suggesting roles for SRC-2 and HBO1 in testicular development and androgen responsiveness.
4 citations
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January 2025 in “Annals of the New York Academy of Sciences” This review explores how spiny mice (Acomys spp.) exhibit unique regenerative healing abilities, with findings indicating that these rodents use specialized injury response mechanisms and proregenerative pathways to enhance tissue repair and regeneration compared to scar-forming mammals.