Clinical Corner: Case Report on Spermatozoa and Chronic Treatment with Finasteride: A TEM and FISH Study

The study investigated the effects of chronic finasteride treatment on spermatozoa using Transmission Electron Microscopy (TEM) and Fluorescence In Situ Hybridization (FISH). Finasteride, a medication commonly used for treating hair loss and benign prostatic hyperplasia, was examined for its potential impact on male fertility. The research focused on the structural and chromosomal integrity of sperm cells. The findings suggested that prolonged use of finasteride might lead to alterations in sperm morphology and chromosomal abnormalities, raising concerns about its implications for male reproductive health. However, the study was limited in scope and further research was needed to fully understand the long-term effects of finasteride on fertility.