48 citations
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December 2019 in “Reproductive Biology and Endocrinology” This review found an increasing trend in research on sperm DNA fragmentation over the past 20 years, especially focusing on lifestyle factors, asthenozoospermia, and varicocele, with the TUNEL technique as a predominant method.
104 citations
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May 2019 in “F1000Research” This review discusses recent research on male infertility causes and treatments, emphasizing the need for further understanding of idiopathic sperm abnormalities and molecular factors to improve patient outcomes; it reports no new clinical results.
August 2024 in “The Journal of Urology” This study updates guidelines for evaluating and managing male infertility, including revised testing recommendations for Y-chromosome microdeletions, use of pelvic MRI, and testicular sperm in nonazoospermic males.
26 citations
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October 2014 in “Andrologia” This review discusses the risk factors and implications of sperm aneuploidy in males, and it reports no new clinical results; the authors highlight the importance of personalized assessment in assisted reproduction.
September 2024 in “Reproduction and Fertility” This review highlights the limited effectiveness of current unlicensed treatments for male subfertility, like hormonal therapy and antioxidants, and emphasizes new drug discovery methods such as high-throughput screening and drug repurposing to improve treatment development for male subfertility.