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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

COVID-19 may harm male fertility and damage the reproductive system.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Ayurveda's descriptions of genetic disorders align with modern genetic understanding.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.

Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.

Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.

Myo-inositol plus α-lactalbumin works better than myo-inositol alone for improving symptoms of PCOS.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

CDP is crucial for lung and hair follicle cell development.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

Gene mutations can cause problems in male genital development.

Finasteride effectively treats mild to moderate hair loss in men aged 18-41, with some side effects.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.