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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Fungi-produced compounds can change plant root growth.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Hair loss needs more research for better treatments.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

CDP is crucial for lung and hair follicle cell development.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Bioprinting could improve wound healing but needs more development to match real skin.

Estrogen therapy can reduce skin aging but has cancer risks.

Stem cell self-renewal is complex and needs more research for full understanding.

Cathepsin L is essential for normal hair growth and development.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.