1 citations
,
March 2023 in “Frontiers in Cardiovascular Medicine” A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
80 citations
,
December 1996 in “Pain” This study found that spinal strychnine enhances low threshold tactile responses in cat dorsal horn neurons, which may mirror pain states in humans that are less responsive to opioid treatments.
17 citations
,
April 2022 in “Frontiers in Pharmacology” This study found that local platelet-rich plasma injection improved mid-term outcomes for carpal tunnel syndrome more effectively than other conservative treatments, although long-term effects and standardization need further research.
31 citations
,
June 2011 in “Movement Disorders” The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
June 2025 in “Neurology India” This case report describes a young girl with a rare association of anti-SRP positive necrotizing autoimmune myopathy and systemic lupus erythematosus, who responded well to corticosteroid treatment.
5 citations
,
January 1998 in “Clinical and experimental dermatology” This article discusses the late presentation of myotonic dystrophy but reports no new clinical findings.
2 citations
,
February 2020 in “Chinese Medical Journal” This case report highlights the missed diagnosis of systemic lupus erythematosus in a pregnant woman, leading to her death despite treatment efforts after cesarean section and epidural anesthesia complications.
2 citations
,
December 2010 in “PubMed” This study reported that a new two-point bending stiffness method effectively correlated with sensory assessments for hair styling gels but not for hair styling sprays, likely due to differences in polymer/hair composites.
33 citations
,
November 2012 in “JAMA Dermatology” In this study, 14 out of 15 women with scalp dysesthesia also had cervical spine disease, and gabapentin improved symptoms for some patients.
19 citations
,
November 2014 in “Journal of Comparative Physiology A” This study found that Cupiennius salei spiders have specialized mechanosensitive hairs on their legs that adaptively respond to joint movements during walking, suggesting a proprioceptive function.
This study presents a case of neuropsychiatric lupus in a 50-year-old woman, highlighting the severe impact on quality of life and the necessity for aggressive treatment to improve outcomes.
13 citations
,
November 1985 in “International Journal of Dermatology” This study examined patients with trichostasis spinulosa and identified distinct differences in the distribution and microscopic appearances of lesions compared to keratosis pilaris and eruptive vellus hair cysts.
1 citations
,
December 1997 in “Archives of dermatology” This report describes a case of trichostasis spinulosa, a condition with pruritic, black papules on the face caused by keratotic plugs with embedded vellus hairs.
5 citations
,
July 2022 in “Orphanet journal of rare diseases” This study found that RSPO1 mutations in patients with a 46XX disorder of sexual development contribute to impaired skin integrity and increased risk of squamous cell carcinoma in areas subject to friction.
March 2023 in “Archives of Physical Medicine and Rehabilitation” This pilot study suggests that high-dose testosterone plus finasteride improved knee extensor strength and muscle size in men with impaired gait after chronic incomplete spinal cord injury.
10 citations
,
January 1925 in “Archives of Dermatology” This article discusses a historical case of a rare skin disorder involving alopecia and follicular plugs reported in 1907; it presents no new findings.
October 2013 in “International Journal of Pediatric Endocrinology/International journal of pediatric endocrinology” This case report describes a boy with hypothalamic hamartoma experiencing pubertas precox and gelastic seizures, where leuprorelin therapy's effect on pubertas precox was controversial, but valproic acid effectively managed gelastic seizures.
January 1999 in “American Journal of Medical Genetics Part A” This case report describes a rare occurrence of ectodermal dysplasia features in a 14-year-old with MBTPS1 gene variants, expanding the known spectrum of related disorders.
January 2020 in “Integrative Medicine Research” April 2018 in “Journal of Investigative Dermatology” African spiny mice can regenerate skin and hair after wounds due to specific tissue mechanics.
October 2022 in “Amplla Editora eBooks” Deep Brain Stimulation helps manage Parkinson's symptoms when medication isn't enough.
This creative piece by Christa Fairbrother poetically explores the experiences of living with arthritis, with no new research findings reported.
227 citations
,
April 2020 in “Cell” This review highlights the ongoing challenges and advancements in developing precise and early intervention strategies for autoimmune diseases and emphasizes the need for more personalized and disease-specific therapies.
15 citations
,
October 2012 in “Journal of child neurology” In this study, two unrelated Honduran patients with Sjögren-Larsson syndrome had the same genetic mutation but displayed different disease severities, suggesting that factors beyond the ALDH3A2 mutation influence clinical outcome.
January 2025 in “Genetics in Medicine Open” In this case report, a 33-year-old male with symptoms resembling Neuromyelitis Optica was treated with 10 mg biotin daily, which may reverse certain ophthalmologic and myelopathy findings. The researchers emphasize the need for further research on biotinidase deficiency in patients misdiagnosed with similar conditions.
June 2022 in “Annals of Indian Academy of Neurology” This case report describes a rare association where herpes zoster infection may have triggered the first attack of NMOSD with systemic vasculitis in a patient, suggesting potential overlaps in immunopathogenesis.
August 2020 in “Current Otorhinolaryngology Reports”
January 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that patients with trichodynia associated with androgenetic alopecia had significantly higher levels of substance P in both tissue and serum compared to healthy controls, suggesting a potential role for this neurotransmitter in the condition's pathogenesis.
13 citations
,
April 2023 in “Biochemical Society Transactions” This mini-review highlights emerging themes on how tissue stiffness, a fundamental material property, influences morphogenetic processes in living organisms, an area gaining increased attention alongside the role of mechanical forces in shaping cell behavior.
December 2007 in “Röntgenpraxis” This review discusses various treatments for androgenic alopecia, highlighting FDA-approved options and other commonly used therapies, but reports no new clinical results.