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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The ginseng market has potential for growth and needs new products and better marketing.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Fat cells help recruit healing cells and build skin structure during wound healing.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.