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PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Polycystic ovary syndrome affects about 6-10% of women, with varying symptoms and the need for standardized global definitions.

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Hair growth is cyclic and influenced mainly by local factors.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Fat-related cells are important for initiating hair growth.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Corporate social responsibility can improve consumer ratings of product performance, especially when the company is seen as benevolent and consumers aren't experts on the product.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.