5 citations
,
November 2015 in “The American journal of pathology” Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.
3 citations
,
September 2017 in “International journal of women’s dermatology” Some domesticated animals have the same genetic skin diseases as humans, which can help doctors understand human genetic mutations.
2 citations
,
March 2020 in “Advances in wound care” Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
2 citations
,
November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
1 citations
,
May 2018 in “Journal of Investigative Dermatology” PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
1 citations
,
January 2017 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
May 2019 in “Journal of Investigative Dermatology” Caffeine can protect scalp hair follicles from damage caused by UV radiation.
May 2018 in “Journal of Investigative Dermatology” Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.
421 citations
,
January 2015 in “Chemical Society Reviews” Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
249 citations
,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
202 citations
,
December 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
162 citations
,
August 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
92 citations
,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
46 citations
,
July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
35 citations
,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
28 citations
,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
12 citations
,
May 2020 in “Dermatology and therapy” A young woman had a rare skin reaction to a medication for her joint disease, and a combination therapy improved her condition.
9 citations
,
January 2019 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
2 citations
,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
1 citations
,
February 2017 in “International journal of anatomy and research” Understanding fetal skin development helps diagnose congenital skin diseases.
May 2024 in “Scientific reports” Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
March 2024 in “Research Square (Research Square)” Twist2 is essential for proper skin healing and hair growth in developing mice.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
232 citations
,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.