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Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Skin fat helps with body temperature control and has other active roles in health.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

Minoxidil can cause severe skin reactions like Stevens-Johnson syndrome in rare cases.

Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.

Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.

Inhibiting PLA2 enzymes may help treat inflammatory skin diseases like psoriasis and dermatitis.

A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.

Injecting newborn mice with a niacin blocker caused skin, gut, and brain damage similar to human pellagra.

Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.

Scientists identified a group of human skin cells with high growth and regeneration potential.

Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.

Aging in men is influenced by genetics and lifestyle, leading to muscle loss, bone issues, and skin damage.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

Researchers created small amber particles for use in bioactive and biocompatible fibers that could help with skin and hair restoration and are safe for infant clothing.

The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.