5 citations
,
March 2023 in “Journal of the American Association for Laboratory Animal Science” In this study, the researchers observed that both standard body and facial depilatory creams caused significant skin injury in mice, with varying effects depending on the mouse strain and exposure time, although both formulations were effective for hair removal.
9 citations
,
May 2014 in “Clinical Cosmetic and Investigational Dermatology” This study suggests that combining GliSODin(®) Skin Nutrients with tazarotene cream significantly benefits facial fine wrinkles, photodamage, moisture, and elasticity compared to tazarotene alone.
38 citations
,
April 2016 in “The Journal of Pathology” This study found that mice lacking alkaline ceramidase 1 with elevated skin ceramide levels showed disrupted skin homeostasis, including altered hair follicle structures, increased water loss, and a hypermetabolism phenotype.
46 citations
,
April 2020 in “Clinical Cosmetic and Investigational Dermatology” This study found that hydroquinone caused structural damage to the skin of rats, while aloe vera reduced this damage, suggesting potential concerns for its use in skin lightening creams.
15 citations
,
February 2020 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is crucial for healthy skin barrier function.
August 2024 in “Veterinary Dermatology” This study reported that topical ω‐0‐acylceramide improved skin barrier function in Jack Russell Terriers with TGM1-deficient autosomal recessive congenital ichthyosis, normalizing skin pH and reducing transepidermal water loss.
9 citations
,
January 2021 in “Mediators of Inflammation” In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.
January 2023 in “Indian journal of pharmacy practice” This study observed that dermoscopic features of skin affected by topical corticosteroids and hydroquinone correlated with histopathological changes, highlighting the importance of awareness regarding their long-term adverse effects.
December 2023 in “International Journal of Health and Pharmaceutical” This study investigated the effects of a derma pen treatment using green betel leaf extract cream on hair development in female Wistar rats, highlighting the antioxidant and anti-inflammatory properties of betel leaves that may aid in hair growth and condition.
August 2021 in “Institutional Repositories DataBase (IRDB)” This study found that rubbing the skin increased caffeine permeation significantly, while rhododendrol showed no enhancement from rubbing, likely due to different distribution patterns in the skin layers.
1 citations
,
July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” This study found that rubbing significantly increased skin permeation of caffeine but not rhododendrol, with the direction of rubbing playing a crucial role in caffeine's enhancement.
20 citations
,
December 2006 in “Archives of dermatology” 2 citations
,
November 2024 in “Acta Dermato Venereologica” In this case report, researchers describe an adult patient with CHILD syndrome whose skin lesions were successfully managed with topical ketoconazole, marking the first known instance of using this treatment without recurrence during follow-up.
January 2026 in “Indus journal of bioscience research.” In this study, Hibiscus rosa-sinensis extract was used to formulate and evaluate herbal cosmetic creams for their antioxidant properties, stability, and effectiveness. The formulations demonstrated strong antioxidant potential, stability under various conditions, and favorable cosmetic qualities, suggesting HRS as a beneficial ingredient in skincare products.
December 2023 in “International Journal of Dermatology” This study observed that among transgender adults undergoing hormone therapy, common skin issues were acne, androgenetic alopecia, and other conditions, highlighting the need for dermatologists in their care; this is noted as the first Colombian and Latin American study on this topic.
January 2023 in “International Journal of Pharmacy and Pharmaceutical Science” In this observational study conducted in Bengaluru, India, among 272 dermatology patients, the authors reported that dermatitis was the most common condition treated with corticosteroids, with a preference for topical applications; desonide was the most frequently prescribed drug.
1 citations
,
April 2023 in “African Scientific Reports” This review summarizes the biological process of melanogenesis and evaluates natural skin-whitening treatments based on their mechanisms affecting melanin production, aiming to inform on the effects and awareness of skin-bleaching creams.
1 citations
,
May 2018 in “International Journal of Advanced Community Medicine” In this research, a new cream containing salicylic acid was developed to treat acne vulgaris, showing no allergic reactions or skin irritation and maintaining stability in controlled conditions, suggesting potential future benefits for skin care and anti-acne treatment.
June 2023 in “Dermatology and Therapy” This study found that for patients with moderate-to-severe chronic hand eczema, combining fractional CO2 laser with halometasone cream was more effective than using halometasone cream alone, with a higher treatment success rate and fewer relapses, though skin pigmentation was a common side effect.
124 citations
,
October 2019 in “Frontiers in Immunology” This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.
24 citations
,
January 2014 in “PubMed” This case report suggests that topical imiquimod cream may be an effective alternative treatment for generalized discoid lupus erythematosus without systemic involvement.
11 citations
,
August 2010 in “Pediatric dermatology” This report details two cases of Lichen spinulosus in the submental area, treated effectively and safely with topical tacalcitol cream.
11 citations
,
May 1957 in “Journal of the American Medical Association” This review clarifies what constitutes an emollient and explains that both cosmetic and pharmaceutical emollients share the same functions, reporting no new research findings.
10 citations
,
January 1967 in “PubMed” This research reports that oral contraceptives may cause melasma in 24-29% of users, with minimal improvement after stopping the drug and limited effectiveness of hydroquinone treatment.
10 citations
,
June 2011 in “PubMed” This article suggests that most topical treatments for acne and unwanted hair growth are safe to use during pregnancy, except for hydroquinone and tretinoin, due to low systemic absorption.
7 citations
,
April 2011 in “Expert review of dermatology” This article reviews practical approaches for managing dermatologic conditions in patients with skin of color and reports no new clinical findings.
5 citations
,
February 2022 in “Animals” This study found that electric shaving was the most effective and safest method for preoperative hair removal in mice, compared to depilatory cream and sodium sulfide, which negatively affected wound healing.
2 citations
,
June 2025 in “Frontiers in Public Health” This study reported that regular mole examinations and UVR protection are crucial for skin cancer prevention, particularly for individuals with fair skin, inflammatory skin conditions, diabetes, and those on photosensitizing medications.
1 citations
,
March 2019 in “Journal of Interdisciplinary Medicine” This case report details a middle-aged man with multiple sclerosis who developed difficult-to-evaluate skin reactions after daclizumab treatment, noting only slight improvement with additional therapies.
November 2023 in “Frontiers in Medicine” This study demonstrated a novel use of tape stripping on a human skin model to simulate the inflammation and barrier damage caused by dry razor shaving, highlighting potential shaving and skin-care formulations that may mitigate such damage.