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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Alopecia areata involves immune response and gene changes affecting hair loss.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Researchers found two genes that may explain why some Casertana pigs don't have hair.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

People with Down syndrome have higher rates of certain immune-related conditions and need special medical attention.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

The project created a standardized system for classifying skin lesions in lab rats and mice.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.