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Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Using steroids can increase the risk of heart problems.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The document concludes that proper diagnosis and management of hair loss in children require a detailed examination and understanding of various hair disorders.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Taking too many vitamin and mineral supplements can cause serious health problems.

The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Platelet-rich plasma (PRP) shows no significant benefit for bone and soft-tissue injuries or wound healing, and its effectiveness may improve with customization.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Men are increasingly using energy-based skin treatments for workplace success, with lasers and other devices effectively improving skin and body appearance.

Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.

Bariatric surgery patients need careful before and after surgery care for safety and long-term health.

The book is a detailed guide on aesthetic surgery with useful content and visuals, but lacks new techniques and a CD, rated 4 out of 5.

Secondary aesthetic surgeries for gender reassignment are generally satisfying and advance overall aesthetic surgery techniques, but psychological support is important.

Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

Proper nutrition can help manage PCOS symptoms and improve overall health.