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A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.

Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.

Low-level laser therapy using near-infrared light may help heart conditions and promote healing by releasing nitric oxide.

Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

PCOS is a common hormonal disorder in women that can lead to serious health problems.

Inherited color dilution in Rex rabbits is linked to DNA methylation changes in hair follicles.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

Boosting mitochondrial energy production with supplements like acetyl-L-carnitine may improve aging-related cellular function and health conditions.

Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Personalized treatment based on detailed tumor analysis successfully managed and reduced the patient's aggressive hair follicle cancer.

Hyaluronic acid injections improve skin thickness and quality, protecting against aging in rats.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Fat-related cells are important for initiating hair growth.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.