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research NASHVILLE - the 4th ISHRS Annual Meeting
This article discusses the rapid advancements in hair restoration surgery presented at ISHRS Annual Meetings and underscores the difficulty of staying updated without attending, but it reports no new experimental findings.
research Schizochytrium sp. Extracted Lipids Prevent Alopecia by Enhancing Antioxidation and Inhibiting Ferroptosis of Dermal Papilla Cells
This study found that lipids extracted from Schizochytrium sp. significantly enhanced the proliferation and survival of dermal papilla cells under oxidative stress, reduced reactive oxygen species, inhibited ferroptosis, and promoted antioxidant genes, which improved hair growth in experimental settings, suggesting a potential treatment for alopecia.
research Scalable and high-throughput production of an injectable platelet-rich plasma (PRP)/cell-laden microcarrier/hydrogel composite system for hair follicle tissue engineering
In this study, researchers used a new method with platelet-rich plasma-loaded microcarriers to enhance dermal papilla cell activity and hair follicle regeneration, achieving significant hair and vessel growth in a mouse model compared to control groups.
research LIFEHOUSE’s Functional Nutrition Examination (Physical Exam, Anthropometrics, and Selected Biomarkers) Informs Personalized Wellness Interventions
During LIFEHOUSE, researchers documented distinct patterns of physical exam findings and biomarker abnormalities in 369 adult employees, which may aid clinicians in recognizing wellness challenges and preventing chronic diseases associated with aging.
research Practice Census finds more people turning to hair restoration surgery
This article provides an update from the ISHRS Practice Census Subcommittee and Media Relations Committee for 2011 but presents no new research results.
research Targeted Determination of Residual Sex Hormones in Cosmetics Using Magnetic Solid-Phase Extraction with Isotope-Labeled Internal Standards by UHPLC-MS/MS
This study developed a method using UHPLC-MS/MS and MSPE to detect trace amounts of sex hormones in cosmetics, finding progestins and estrogens in some products, and performed a preliminary safety evaluation for residual progesterone in hair loss prevention cosmetics.
research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.
research Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system
In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.
research A multi-centre, double-blind, randomised, vehicle-controlled study for a quantitative estimation of hair re-growth in male subjects with androgenetic alopecia treated over 6 month with two ethanolic PSK 3841 solutions (2.5% and 5%)
research 895 Isoproterenol directs human hair follicle-associated pluripotent (hHAP) stem cells to differentiate to cardiac muscle cells
According to this study, human scalp hair follicles containing pluripotent stem cells demonstrated the ability to differentiate into cardiac muscle cells and other cell types, suggesting potential applications in heart and nerve regeneration.
research Ethanol extract of medicinal herbal mixture accelerates hair growth and melanogenesis in vivo and in vitro
In this study with C57BL/6 mice, SHJ extract was associated with increased hair growth and density, suggesting potential use in hair care cosmeceuticals, while also enhancing melanin production in melanoma cells.
research 562 Neuroendocrinology of human scalp hair follicles: Growth hormone-releasing hormone (GHRH) stimulates hair growth and controls a fully functional intrafollicular hypothalamic-pituitary-somatotropic (HPS) signaling axis
This study found that human scalp hair follicles produce neurohormones and responded to GHRH stimulation by prolonging hair growth, suggesting a functional peripheral HPS neuroendocrine signaling axis in the skin.
research Psychotrichology
Emotional states significantly affect hair growth and hair disorders.
research Reproducibility of high-resolution laser speckle contrast imaging to assess cutaneous microcirculation for wound healing monitoring in mice
This study found that high-resolution laser speckle contrast imaging devices provide good reproducibility for assessing skin perfusion in mice but not for measuring haemoglobin oxygenation.
research Small Molecules Accelerate Skin Wound Healing: Shikonin Efficacy and Mechanism of Action in Mice
In this study, researchers observed that shikonin promotes wound healing in a mouse burn model by enhancing skin cell proliferation and fibroblast activity through the PI3K/AKT signaling pathway, suggesting its potential as a therapeutic treatment for skin injuries.
research A Novel Hair Restoration Technology Counteracts Androgenic Hair Loss and Promotes Hair Growth in A Blinded Clinical Trial
This study reported that Tomorrowlabs HIF strengthening factor [HSF] hair restoration technology significantly improved hair thickness, density, shine, and elasticity, while reducing hair loss by an average of 66.8% and enhancing hair growth by up to 32.5% in subjects with androgenic alopecia over nine months.
research Shrinking the Specialty of Hair Restoration Surgery
This abstract discusses issues related to negative marketing within the ISHRS but reports no new research findings.
research Highlights of the Japanese Society of Hair Restoration Surgery's annual scientific meeting
This meeting summary reports on a gathering of the Japanese Society with presentations primarily in Japanese and provides no new scientific findings.
research Hair??s the long and short of it
research The MHS Hair Restoration Protocol: A Systems-Biology Integration of Nutritional Support, Microbiome Modulation, and Targeted Topical ECS Therapeutics
This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.
research Hair Plugs Bethesda
This promotional text about hair replacement options near Lauderdale Lakes argues against hair plugs, implants, laser transplants, and robotic surgery but provides no clinical research findings.
research Scalp Micropigmentation: A Clinicopathologic Correlation
In this study, the researchers found that trichoscopy can effectively visualize scalp micropigmentation, identified by homogenous, grey to black circular dots similar to closely cut hair, potentially reducing the need for invasive procedures.
research Filtration of Transgenic Sheep Skin Fibroblasts with KAP6.1-GFP-polymerized Spider Dragline Silk Protein Gene(4S)
This study successfully established a transgenic sheep fibroblast cell line expressing the spider dragline silk protein gene, laying groundwork for developing transgenic sheep with this capability in hair follicles.
research Self-assembling peptide hydrogel scaffolds support stem cell-based hair follicle regeneration
In this study, the RADA-PRG hydrogel enhanced SKP proliferation, survival, and gene expression, effectively supporting hair follicle regeneration in mice.
research 1410 Single-cell RNA sequencing reveals POUF51 and HES3 as regulators of the stem cell population in psoriasis
This research reexamined transcriptomic data to study stem and progenitor cell proliferation in psoriasis, finding that the number of committed progenitor cells increased eight-fold in psoriatic skin without altering stem cell numbers, potentially identifying new therapeutic targets.
research 653 Substance P ameliorates epidermal thickness, basal cell density, and asymmetric stem cell self-renewal in skin with decreased sensory innervation
Substance P helps restore skin thickness and cell renewal when sensory nerves are reduced.
research The IBHRS Is Up and Running!
This announcement from the President of the American Board of Hair Restoration Surgery reports the formation and incorporation of the International Board of Hair Restoration Surgery, but offers no new research findings.
research Decision letter: Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets
This study suggests that Sonic hedgehog from hair follicles may support the proliferation of dentate neural stem cells in mice through transport by platelets during the perinatal period.
research FORMULATION AND CHARACTERIZATION OF NOVEL Ziziphus Spina-Christi HERBAL PREPARATION AS A HAIR TONIC
In this study, the researchers formulated an herbal shampoo and found it exhibited excellent cleansing properties and foam stability, comparable to commercial shampoos, suggesting it as a safe and cost-effective alternative to marketed formulations.