131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
76 citations,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.
26 citations,
July 2012 in “Journal of family planning and reproductive health care” The document says that hirsutism in women usually needs hair removal and hormone treatment to manage symptoms and improve well-being.
24 citations,
March 2003 in “Best Practice & Research Clinical Endocrinology & Metabolism” Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
12 citations,
October 2018 in “Aging male/The aging male” Higher BMI and lower testosterone are linked to more aggressive prostate cancer.
11 citations,
January 2020 in “Medical Journal Armed Forces India” Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
11 citations,
July 2019 in “International journal of women’s dermatology” Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.
9 citations,
January 2022 in “Reproductive Biology and Endocrinology” High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
7 citations,
August 2023 in “EClinicalMedicine” Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.
5 citations,
September 2021 in “Journal of The American Academy of Dermatology” Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.
5 citations,
July 2021 in “medRxiv (Cold Spring Harbor Laboratory)” Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.
4 citations,
March 2018 in “Systems biology in reproductive medicine” Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.
4 citations,
January 2018 in “JBRA assisted reproduction” Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
3 citations,
October 2022 in “International Journal of Impotence Research” Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.
3 citations,
January 2018 in “Frontiers in bioscience” Daily subcutaneous testosterone effectively restores testosterone levels in men.
2 citations,
December 2021 in “Cureus” Most women with Polycystic Ovary Syndrome (PCOS) have skin issues like excessive hair, acne, or hair loss. Hormone imbalances are common, and age, certain hormones, and hormone ratios can predict acne. Obesity, infertility, and high cholesterol are also common in these women.
2 citations,
October 2021 in “Journal of Cosmetic Dermatology” Finasteride is more effective and satisfactory than montelukast for treating moderate acne in women.
2 citations,
May 2021 in “Journal of the Endocrine Society” Men with high genetic risk for Polycystic Ovary Syndrome (PCOS) have increased chances of obesity, type 2 diabetes, heart disease, and hair loss, showing PCOS risk factors can affect both genders.
1 citations,
December 2022 in “Biomedicines” Middle-aged women with PCOS often continue to experience symptoms related to high androgen levels, like unwanted hair growth.
1 citations,
December 2022 in “Gynecological Endocrinology” The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.
1 citations,
May 2020 in “Journal of The American Academy of Dermatology” Women with hair loss should be checked for PCOS, as it's often related and early diagnosis can help with treatment.
1 citations,
February 2017 in “Journal of gynecology and womens health” The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
1 citations,
July 2006 in “Acta obstetricia et gynecologica Scandinavica” Physical activity significantly improved symptoms of PCOS in a patient.
September 2024 in “Medicina” Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.
May 2024 in “Journal of clinical medicine” Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
March 2024 in “Middle East Fertility Society Journal/Middle East Fertility Society Journal ” PCOS patients have more central body fat, which can be effectively measured using DEXA.
January 2024 in “Medicina” Statins may help treat PCOS by lowering androgen levels and improving cholesterol.
October 2023 in “Journal of the Endocrine Society” Losing weight, possibly through bariatric surgery, is key to improving PCOS and hyperandrogenism symptoms in obese patients.
October 2023 in “Journal of the Endocrine Society” A woman's ovarian fibroma caused high testosterone levels, which normalized after surgery.
August 2023 in “Journal of Clinical Medicine” Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.