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Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.

New treatments for male hypogonadism are effective and should be personalized.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Minoxidil effectively treats severe hypertension, but watch for side effects.

Dermatologists need to understand African American hair-care practices to better treat their hair and scalp disorders.

Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.

The coronal approach is effective and safe for reducing eye bulging in Graves' eye disease.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

TrichoScan is a reliable method for measuring hair growth and is useful for assessing hair loss treatments.

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

Dermal papilla cells help wounds heal better and can potentially grow new hair.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Inactive hair follicle stem cells help prevent skin cancer.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

RTA 408 cream protects mice from radiation skin damage.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

Laser hair removal improves quality of life but emotional benefits decrease over time, suggesting more treatments are needed for lasting effects.

Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

All three treatments reduce hirsutism, but spironolactone works best long-term.