13 citations,
June 2018 in “Current Urology Reports” Hair loss drugs may cause sexual issues and infertility in men.
15 citations,
March 2020 in “Anais Brasileiros De Dermatologia” Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
12 citations,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.
8 citations,
December 2016 in “Revista Medica De Chile” Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.
3 citations,
September 2023 in “International journal of impotence research” Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
1 citations,
May 2019 in “The Journal of Sexual Medicine” Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.
41 citations,
October 2012 in “Australian and New Zealand Journal of Psychiatry” Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
12 citations,
January 2013 in “Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz” Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
July 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.
December 2013 in “Reactions Weekly” Some men taking finasteride for hair loss experienced anxiety, depression, and sexual problems, which sometimes continued after stopping the medication.
19 citations,
April 2020 in “Dermatologic Therapy” Dutasteride works better than finasteride for hair loss, with both being safe to use.
14 citations,
January 2019 in “Skin appendage disorders” PFS might be a delusional disorder with potential to become mass psychogenic illness.
June 2024 in “Trends in Urology & Men s Health” Post-finasteride syndrome is rare but serious and should be taken seriously.
20 citations,
August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
20 citations,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
17 citations,
September 2020 in “Journal of Endocrinological Investigation” Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
1 citations,
October 2017 in “The Journal of Urology” Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.
7 citations,
January 2019 in “The Aging Male” Post-finasteride syndrome's existence is uncertain; more research needed.
11 citations,
January 2018 in “International Journal of Trichology” The true incidence of post-Finasteride syndrome is unclear, and more research is needed.
November 2012 in “Endocrine Practice” Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
44 citations,
July 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
23 citations,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
20 citations,
June 2015 in “Hormone Molecular Biology and Clinical Investigation” Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
14 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” Some nonsurgical hair loss treatments are effective, especially if started early.
Most American men experience hair loss by age 50, with limited effective treatments available and new options not expected soon.
May 2003 in “Facial Plastic Surgery Clinics of North America” Hair loss can be treated with medications like minoxidil and finasteride or surgery, but treatment effectiveness varies by alopecia type and accurate diagnosis is important.
January 2021 in “International Journal of Research in Dermatology” Combination therapies are more effective for treating androgenetic alopecia than single treatments.
2 citations,
January 2011 in “Clinical medicine insights” Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.
14 citations,
December 2016 in “Sexual Medicine” Finasteride side effects in young men may be linked to specific gene variations.
10 citations,
February 2020 in “Endocrine” Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.