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High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Skin doctors should recognize and treat conditions like hair-pulling and skin-picking early, often using therapy and medication, to help 50-70% of patients.

A new tool can analyze hair to detect changes due to hormones, genetics, and aging.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Hair loss in men is common, treatable, but not curable.

Neurosteroids show promise for treating epilepsy and more research is needed.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Zinc is effective for treating various skin conditions, including warts and acne.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Hair loss can cause serious mental health problems and treating it requires a team of experts.

A new mutation in the DCAF17 gene was found in a Chinese family, causing Woodhouse-Sakati syndrome and diabetes.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

The document concludes that cosmetic surgery is still mainly a practice for women and the gender gap in this field is expected to continue.

Genetics and hormones cause hair loss; finasteride treats it safely.

Certain drugs that block specific enzymes can help treat prostate diseases.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.