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Primary care doctors should address female sexual dysfunctions to improve women's sexual health and life quality.

New genes and pathways are important for testosterone production and male sexual development.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.

Zinc is important for growth and health in animals, plants, and humans, and not having enough can cause various problems.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

Neuregulin3 affects cell development in the skin and mammary glands.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Hormonal imbalances are a key cause of missed menstrual periods in women.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.

The document reports three sisters with Woodhouse-Sakati syndrome showing typical symptoms and unusual gynecological anomalies.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

The document explains different hair loss types and treatments, emphasizing diagnosis through examination and tests, and specific treatments for each condition.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.