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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Diagnosing PCOS is challenging due to its complex and varied symptoms.

A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.

Long-term finasteride use doesn't change bone density or metabolism.

Hirsutism in women often indicates a hormonal imbalance and can be managed with a combination of hormonal treatments and hair removal methods.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

DHT, a testosterone byproduct, causes male pattern baldness.