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Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.

Choosing the right starting dose of Clomiphene Citrate for ovulation induction in PCOS women is challenging; higher BMI and hormone levels may indicate resistance to the standard dose.

Genes and hormones cause hair loss, with four genes contributing equally.

High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Anti-Müllerian hormone is a specific marker for ovarian issues in women with conditions like PCOS.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Gingivitis may increase a hormone linked to ovarian function in women with a certain ovary condition, and treating gum disease could help manage it.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Long-term finasteride use doesn't change bone density or metabolism.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.