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PCOS is a common hormonal disorder with symptoms like irregular periods and excess hair growth, managed with lifestyle changes and medications.

Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.

Sex hormones affect brain cells differently in males and females.

New treatments targeting fibrosis could improve urinary symptoms in BPH.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Good preoperative assessment is crucial for safe and effective eyelid and brow cosmetic surgery.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Warts in HIV-positive men can have serious abnormal cell growth, needing careful analysis and treatment to prevent cancer.

Fear of hair-related issues causes significant mental distress, especially in high-stress women.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.