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Leydig cells can cause testosterone-secreting adrenal tumors in women.

Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.

The document concludes that more research is needed to fully understand the causes of PCOS.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Laser hair removal is effective for dark hair but needs improvement for nonpigmented or fine hairs.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.