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Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.

Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Monitoring for adverse effects in clinical treatments is crucial.

Tamsulosin increases the risk of floppy iris during eye surgery.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.

Monocyclic aromatic compounds are important for developing various drugs and treatments.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Trichotillomania, a disorder where people compulsively pull out their own hair, often starts around age 12, is more common in adult females, and can be treated with behavior therapy and medication.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Trichotillomania is more common than previously thought, with increasing diagnosed cases.

Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.

Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.

Cannabinoids may help treat various skin conditions.

Increasing TSPO in the brain reduces anxiety and depression.

Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.