10 citations,
November 2021 in “Biomedicines” Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.
1 citations,
November 2020 in “Asian Journal of Pharmaceutical and Clinical Research” Nanoparticles may improve treatment for lung disease by targeting cells better and reducing side effects.
46 citations,
May 1997 in “British journal of dermatology/British journal of dermatology, Supplement” Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.
1 citations,
April 2015 in “Iranian Journal of Clinical Infectious Diseases” H. pylori infection is not linked to PCOS or infertility.
39 citations,
June 1982 in “The BMJ” Blood tests confirmed a baby in the womb had a CMV infection.
The study on systemic lupus erythematosus (SLE) in India, involving 40 patients, found that the mean age of onset was 23.3 years with a female to male ratio of 19:1. Common skin lesions included malar rash (77.5%), photosensitivity (70%), and non-scarring alopecia (60%). Systemic manifestations frequently observed were arthritis (77.5%) and nephritis (30%). Among patients with only cutaneous manifestations, a significant number had positive serological markers such as antinuclear antibody (85%) and anti-double-stranded DNA (57%). The findings suggest that early identification of SLE through skin lesions and serological profiles can precede systemic symptoms, highlighting the importance of environmental factors in the Indian context.
42 citations,
December 2004 in “Paediatric Respiratory Reviews” Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.
39 citations,
October 2018 in “Lupus Science & Medicine” Different types of hair loss in lupus need careful diagnosis for proper treatment.
30 citations,
October 2013 in “Lupus” Hair loss in lupus is different from hair loss in alopecia areata and may indicate lupus activity.
20 citations,
January 1998 in “Dermatology” Newborn acne may be linked to family history of high male hormone levels.
19 citations,
January 2012 in “Dermato-endocrinology” Moderately high prolactin levels do not cause hair loss in women.
11 citations,
July 2020 in “Anais Brasileiros de Dermatologia” Dermoscopy helps diagnose syphilitic alopecia, and treatment with penicillin can regrow hair.
10 citations,
July 2012 in “International Journal of Dermatology” Syphilis can cause hair loss and should be considered in unexplained cases.
7 citations,
January 2018 in “International Journal of Dermatology” Syphilis can cause hair loss without other symptoms and should be considered when diagnosing unexplained hair loss.
2 citations,
October 2010 in “Reviews in Medical Microbiology” Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.
1 citations,
January 2016 in “Case Reports in Clinical Medicine” Hair loss in HIV patients should be tested for syphilis as well.
April 2024 in “Journal of clinical medicine” Recognizing specific skin features helps diagnose and manage lupus erythematosus effectively.
3 citations,
May 2022 in “Journal of Infection” People with no symptoms or mild COVID-19 have lower antibody levels, increasing their risk of getting COVID-19 again.
26 citations,
April 2016 in “Respiratory Medicine” Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
25 citations,
October 1976 in “The BMJ” A woman showed neurological symptoms from psittacosis linked to bird exposure, improving after antibiotic treatment.
2 citations,
December 2023 in “Mediterranean Journal of Rheumatology” This study compared the clinical features and autoantibody profiles of late onset (≥50 years) and young onset (18-49 years) Systemic Lupus Erythematosus (SLE) in 305 patients. Late onset SLE patients (n=69) had a mean age of 59.42 years and showed higher frequencies of interstitial lung disease (14.5%), pancytopenia (13%), and diffuse alveolar hemorrhage (4.3%). Significant differences between the groups included higher rates of photosensitivity, malar rash, excessive hair loss, Raynaud's phenomenon, lymphadenopathy, nephritis, and specific autoantibodies (anti-dsDNA, anti-nucleosome, anti-Sm, Ribosomes P0) in young onset SLE. The study concludes that late onset SLE has distinct clinical and serological characteristics compared to young onset SLE.
1 citations,
July 2023 in “Al-Azhar Medical Journal” This study assessed serum levels of antigliadin antibodies (IgA and IgG) in 30 patients with alopecia areata (AA) compared to 30 healthy controls. Results showed that antigliadin IgA was positive in 26.7% of AA patients with severe disease, while IgG was positive in all AA patients and 6.7% of controls. There was a significant difference in IgA and IgG levels between patients and controls, with higher values in patients. The study concluded a strong association between antigliadin antibodies and AA severity, recommending serological screening for celiac disease in AA patients due to the high sensitivity and specificity of these antibodies.
1 citations,
February 2023 in “International Journal of Rheumatic Diseases” This case-based review analyzed three instances of tuberculosis (TB) mimicking systemic lupus erythematosus (SLE) flare, with patients aged 27 to 32 years. These cases lacked typical SLE features like butterfly erythema, lupus hair, alopecia, or proteinuria. The study found that TB could induce the production of various autoantibodies, such as anti-nuclear and anti-double-stranded DNA antibodies, which are usually seen in SLE. However, these autoantibodies did not change the clinical or radiographic presentation of TB and were not present after the infection resolved. The resistance of SLE-like symptoms to steroid and immunosuppressive treatments suggested an infectious cause. The findings highlight the importance of considering active TB in patients with SLE-like symptoms, especially when specific serological markers and hypocomplementemia are present.
1 citations,
January 2020 in “Turk Dermatoloji Dergisi” A woman developed a skin condition called Pemphigus Vulgaris after a treatment to help with hair loss.
May 2023 in “Sučasna pedìatrìâ. Ukraïna” An 11-year-old child with total hair loss may have a genetic autoimmune disease, and the outlook for hair regrowth is not good.
March 2023 in “International Journal of Dermatology” A 51-year-old woman developed a nonpruritic urticated rash following a COVID-19 infection, which led to a diagnosis of systemic lupus erythematosus (SLE) with associated symptoms including pericarditis, hypertension, and renal impairment. Histopathology and serology indicated possible neutrophilic urticarial dermatosis (NUD) or hypocomplementemic urticarial vasculitis syndrome (HUVS). The patient later experienced central nervous system vasculitis, treated successfully with methylprednisolone, intravenous immunoglobulin, and plasma exchange. This case underscores the importance of considering serious systemic diseases in patients with nonpruritic urticated rashes and highlights the need for comprehensive serological testing and biopsy for accurate diagnosis and early treatment.
November 2019 in “Pubvet” The document concludes that atopic dermatitis in dogs is managed with various treatments including antipruritics, supplements, and possibly immunotherapy.
2 citations,
January 2009 in “Clinical and Experimental Dermatology” A small forehead lesion led to the discovery of a significant brain arteriovenous malformation in a young girl.
3 citations,
July 2014 in “QJM” A 35-year-old man had patchy hair loss that was actually due to syphilis, not alopecia areata.
Children under 18 had milder SARS with no deaths, but teenagers faced higher severe illness risk, and effective treatments were uncertain.