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Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

No effective treatment exists to stimulate hair growth in atrichia with papular lesions.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.